Breast cancer is a significant health concern worldwide, including in Saudi Arabia, where it is the most common cancer among women. Despite the importance of early detection through screening, the uptake of breast cancer screening remains relatively low among Saudi women. This study aims to explore the perceived barriers to breast cancer screening among Saudi women in primary care settings. Through qualitative interviews and surveys, factors such as cultural beliefs, lack of awareness, fear of diagnosis, and logistical challenges are investigated. Understanding these barriers is crucial for designing targeted interventions to promote breast cancer screening uptake and improve women's health outcomes in Saudi Arabia.